Biochem/physiol Actions

Primary TargetCPT1

General description

A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 µM and 40 µM, respectively.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Xu, F.Y., et al. 2003. J. Lipid Res.44, 415.

Packaging

Packaged under inert gas

2 mg in Glass bottle

Physical form

A 50 mM (2 mg/118 µL) solution of Etomoxir (Cat. No. 236020) in H₂O.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

Warning

Toxicity: Standard Handling (A)